Lezhi Chen (陈乐知) is currently an undergraduate student at the College of Electrical Engineering, Sichuan University. His current research interests lie primarily on Computational Systems Biology and Machine Learning (Generative Models, Graph Neural Networks). He is also very interested in Statistical Physics, Biological Physics, and Complex Systems.

陈乐知，四川大学本科生。他目前在北京大学国际机器学习中心实习，在周沛劼老师的指导下学习细胞动力学。他还是四川大学计算机学院的实习生，在琚玮老师的指导下进行空间转录组学、图聚类相关研究。他当前的研究兴趣主要围绕生物学，从计算与理论两方面展开：在计算方面，他主要关心机器学习（生成模型、图神经网络）在计算生物学中的应用；在理论方面，他主要对从统计物理的视角研究生物学机理感兴趣（尚在学习中，目前所知甚少哈哈）。此外，在工程方面，他还积极与临床医生合作，针对临床研究中的实际问题进行数据挖掘。日常生活中，他喜欢推galgame，rpg和看动漫。如果你对上述领域感兴趣，非常欢迎随时联系，他非常喜欢和不同背景的科研工作者交流学习！

Email: chenlezhi@stu.scu.edu.cn

Selected Publications

Computational Biology:

Looking forward to future interesting research

Systems Biology:

Looking forward to future interesting research

十分感兴趣，不过现在还在打热力学与统计物理基础，路漫漫其修远兮~

Bioinformatics:

Looking forward to future interesting research

🔥 News

2025.11: 🎉🎉 One paper has been accepted by AAAI 2026 !!

📖 Educations

2023.09 - 2027.06, B.S. in Automation, College of Electrical Engineering, Sichuan University

💻 Internships

2026.01 - now, Center for Machine Learning Research, Peking University

Computational Systems Biology, Cellular Dynamics

Supervised by: Prof.Peijie Zhou
2024.12 - 2026.02, College of Computer Science, Sichuan University

Spatial Transcriptomics, Graph Neural Networks

Supervised by: Prof.Wei Ju

📝 Publications

2026

stHGNN: Deciphering Spatial Transcriptomics via Dual Hypergraph Enhancement

Lezhi Chen*, Jinghong Tang*, Siyu Yi, Yifan Wang, Ziyue Qiao, Jiancheng Lv, Wei Ju

Under review

2025

MOST: Modularity-guided Domain Identification in Spatial Transcriptomics Data

Lezhi Chen, Siyu Yi, Wei Zhang, Wei Liu, Mingyang Li, Yifan Wang, Ziyue Qiao, Bin Guo, Xianggen Liu, Jiancheng Lv, Wei Ju

Under review
Evidence-aware Integration and Domain Identification of Spatial Transcriptomics Data

Wei Zhang, Siyu Yi, Lezhi Chen, Yifan Wang, Ziyue Qiao, Yongdao Zhou, Wei Ju

AAAI 2026, CCF-A
stUAI: Uncertainty-aware Clustering of Spatially Resolved Transcriptomics Data

Wei Ju, Lezhi Chen, Siyu Yi, Wei Zhang, Yifan Wang, Yanran Zhu, Ziyue Qiao, Jiancheng Lv

Under review

🎖 Honors and Awards

2025.10, Individual second-class scholarship, Sichuan University